Effect of Carbomer Concentration on the Characteristics of Peel-Off Gel Mask Containing Fragrant Citronella Leaves (Cymbopogon nardus L. Rendle) and Antibacterial Activity Test Against Staphylococcus aureus

Erfan Tri Prasongko; Septiawan  Adi Nugroho; Lidia Novitasari

Authors

Erfan Tri Prasongko IIK Bhakti Wiyata
Septiawan Adi Nugroho
Lidia Novitasari Fakultas Farmasi, Institut Ilmu Kesehatan Bhakti Wiyata

Keywords:

antibacterial, Carbomer, Citronella leaf extract, Peel-off gel mask, Staphylococcus aureus

Abstract

Citronella leaves are efficacious as antibacterial because they contain flavonoids, so they have the potential to be developed into a peel-off gel mask for anti-acne treatment. Peel-off gel masks can be formulated in the presence of a gelling agent. Carbomer was chosen as a gelling agent because it does not irritate the skin. The research method used experimental, as well as One Way ANOVA and LSD data analysis. Results: FI, FII, FIII organoleptic test with semisolid gel form, greenish brown in color, characteristic odor; homogeneity test FI, FII, FIII homogeneous preparations; pH test FI, FII, FIII there is a significant difference in LSD; the FI, FII, FIII dispersion test showed a significant difference in LSD; the FI, FII, FIII adhesion test showed a significant difference in LSD; dry time test FI, FII, FIII there is a significant difference in LSD; irritation acceptability test and liking there was no significant difference in Kruskal-Wallis; Test activity FI, FII, FIII there is a significant difference in LSD. Conclusion: There is an effect of variations in carbomer concentration on the characteristics of the preparation and the antibacterial activity test on Staphylococcus aureus bacteria, and there is no effect of variations in the concentration of carbomer on the acceptability test of irritation and preference tests.

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